Steady-state plasma levels of amlodipine are reached after to days of consecutive daily dosing. Cautions Do not take this medicine if you have had an allergic reaction to it or are allergic to any ingredient in this product. It may be easier to take your dose if you do norvasc comprare on-line in magazzino it at the same time every day, such as with breakfast, dinner, or at bedtime. The antihypertensive efficacy of Norvasc has been demonstrated in total of 15 double-blind, placebo-controlled, randomized studies involving 800 patients on Norvasc and 538 on placebo. DIGOXIN: Co-administration of Norvasc with digoxin did not change serum digoxin levels or digoxin renal clearance in normal volunteers. Maintenance of the blood pressure effect over the 24-hour dosing interval was observed, with little difference in peak and trough effect.